Non-adherence is complex and multi-determinant, and is frequently intentional amongst patients with HIV. Barriers to compliance that are consistently reported by patients include: “don’t understand treatment and/or suspicious of medication”. This suggests that a communication-based intervention designed to demystify HAART medications, i.e. to improve patients understanding of their medication and of the consequences of non-adherence, might improve adherence. Indeed, this has been shown to be the case. I believe any successful intervention will involve a significant component of peer-to-peer communication, as opposed to being reliant solely on doctor-disseminated materials. Communications technology is advancing at an unprecedented rate (see our twitter account), and the scope for peer-to-peer communications is massive.